Determination of somatic status of girls with chronic vulvovaginitis in the neutral period of life

The objective: a determination of the spread somatic pathology and polymorphism MSM6 gene in development chronic recurrent vulvovaginitis girls. Materials methods. study involved 54 girls 1–6 years old. Inclusion criteria: complaints patients on itching or pain genital area, dysuria, presence synechiae vulva, clinical manifestations vulvitis during visual examination. General laboratory diagnostic methods were used (blood test, general urine analysis with ketone bodies, bacterioscopic examination vaginal smears, culture for flora antibiotic sensitivity, glucose levels blood serum urine). For diagnosis lactose malabsorption by polymerase chain reaction, mutation MCM6 was studied, genetic marker which is C (-13910). Results. status presented gastrointestinal digestive tract 68.5 % cases, atopic dermatitis – 53.7 %, diseases respiratory system 33.3 infectious processes kidneys urinary 24.1 %. 77.6 had nondiabetic acetone syndrome, 75.9 dysmetabolic nephropathy. revealed homozygosity (C/C) 26.1% patients, heterozygosity (C/T) - 56.5 absence (T/T) 8 (17.4 %). Conclusions. In neutral period life vulvovaginitis, non-infectious forms disease found, not independent pathology, but associated other pathological metabolic disorders. Taking into account obtained data malabsorption, we consider to include algorithm verification lactosuria load.